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Spillover in the spotlight
1Department of Neuroscience, University of California, San Diego, La Jolla 92093-0608, USA. jisaacson@ucsd.edu
Current Biology : CB
|July 19, 2000
Abstract:
Fast neurotransmission in the brain is typically mediated by local actions of transmitters at ionotropic receptors within synaptic contacts. Recent studies now reveal that, in addition to point-to-point signaling, amino-acid transmitters mediate diffuse signaling at extrasynaptic metabotropic receptors.