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DNA vaccines: a key for inducing long-term cellular immunity
S Gurunathan1, C Y Wu, B L Freidag
1Clinical Immunology Section, Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Current Opinion in Immunology
|July 19, 2000
Abstract:
Over the past few years, major advances in several areas of immunology have provided a foundation for the rational design of vaccines against diseases requiring cellular immunity. Among these advances are the cellular mechanisms by which DNA vaccines can sustain long-term humoral and cellular immunity.