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A practical large-scale synthesis of 17alpha-acetoxy-11beta-(4-N,
P N Rao1, C K Acosta, M L Bahr
1Department of Organic Chemistry, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245-0549, USA. pnrao@sfbr.org
Steroids
|July 19, 2000
Abstract:
A new practical synthesis of 17alpha-acetoxy-11beta-(4-N, N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione (CDB-2914) is described. The synthesis gives easily isolable solids at all steps and is amenable to large-scale process.