Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Helminth C-type lectins and host-parasite interactions.

A Loukas1, R M Maizels

  • 1Molecular Parasitology Unit, Queensland Institute of Medical Research, 300 Herston Road, Brisbane 4029, Queensland, Australia. alexl@qimr.edu.au

Parasitology Today (Personal Ed.)
|July 20, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Categorizing E-cigarette-related tweets using BERT topic modeling.

Emerging trends in drugs, addictions, and health·2025
Same author

Transgenesis in parasitic helminths: a brief history and prospects for the future.

Parasites & vectors·2022
Same author

<i>In Vivo</i> Nematicidal Potential of Camel Milk on <i>Heligmosomoides Polygyrus</i> Gastro-intestinal Nematode of Rodents.

Helminthologia·2019
Same author

Chemical analyses and anthelmintic effects of Artemisia campestris essential oil.

Veterinary parasitology·2018
Same author

Flavored e-cigarette use: Characterizing youth, young adult, and adult users.

Preventive medicine reports·2016
Same author

Parasitic helminth infections and the control of human allergic and autoimmune disorders.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2016

C-type lectins (C-TLs) are proteins involved in immunity. Helminth C-TLs from nematode parasites may help worms evade the host immune system.

Area of Science:

  • Immunology
  • Parasitology
  • Biochemistry

Background:

  • C-type lectins (C-TLs) are carbohydrate-binding proteins crucial for vertebrate immunity and hemostasis.
  • Helminth C-type lectins (C-TLs) identified in nematode parasites share similarities with mammalian immune lectins.
  • These similarities suggest a role for helminth C-TLs in host-parasite interactions, particularly immune evasion.

Purpose of the Study:

  • To review the current research on helminth lectin biology.
  • To explore the potential functions of C-type lectins (C-TLs) in parasitic worms.
  • To understand how parasitic worms might utilize C-TLs during their life cycles.

Main Methods:

  • Literature review of existing studies on helminth lectins.
  • Comparative analysis of C-type lectin (C-TL) sequences and structures between helminths and mammals.

Related Experiment Videos

  • Discussion of potential mechanisms for immune evasion mediated by helminth C-TLs.

    • Main Results:

    • Helminth C-type lectins (C-TLs) exhibit significant sequence and structural homology to mammalian immune lectins.
    • This homology implies that helminth C-TLs likely play a role at the host-parasite interface.
    • Parasitic worms may employ C-TLs as a strategy for immune evasion.

    Conclusions:

    • Helminth C-type lectins (C-TLs) represent a promising area of research for understanding host-parasite interactions.
    • Further investigation into helminth C-TLs could reveal novel targets for therapeutic intervention.
    • Understanding the function of these lectins is key to developing strategies against parasitic worm infections.