Jove
Visualize
Contact Us

Related Experiment Videos

Paternalism.

J D Capozzi1, R Rhodes

  • 1Department of Orthopaedics, Mount Sinai Medical Center, New York, NY 10128, USA.

The Journal of Bone and Joint Surgery. American Volume
|July 20, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Decisions on Innovation or Research for Devastating Disease.

The American journal of bioethics : AJOB·2021
Same author

A paradigm for understanding trust and mistrust in medical research: The Community VOICES study.

AJOB empirical bioethics·2018
Same author

Adsorbent 2D and 3D carbon matrices with protected magnetic iron nanoparticles.

Nanoscale·2015
Same author

Application of rapid microbiological methods for the risk assessment of controlled biopharmaceutical environments.

Journal of applied microbiology·2014
Same author

A phase I trial of oral ridaforolimus (AP23573; MK-8669) in combination with bevacizumab for patients with advanced cancers.

Clinical oncology (Royal College of Radiologists (Great Britain))·2013
Same author

Decreased regional gray matter volume in S' allele carriers of the 5-HTTLPR triallelic polymorphism.

Molecular psychiatry·2010
Same journal

Do Younger Patients Undergoing Transfibular Total Ankle Arthroplasty Achieve Outcomes Comparable with Those of Older Patients? Interpreting Nonsignificant Differences in Clinical Research: Commentary on an article by Kevin A. Schafer, MD, et al.: "Clinical and Radiographic Outcomes at a Mean of 7 Years Following Primary Transfibular Total Ankle Arthroplasty in Younger and Older Patients".

The Journal of bone and joint surgery. American volume·2026
Same journal

Clinical and Radiographic Outcomes at a Mean of 7 Years Following Primary Transfibular Total Ankle Arthroplasty in Younger and Older Patients.

The Journal of bone and joint surgery. American volume·2026
Same journal

Quantifying Protrusio Risk in the Metastatic Acetabulum: A Step Toward Precision: Commentary on an article by Will Jiang, BS, et al.: "Development of a Radiographic Scoring System to Estimate Acetabular Protrusion Risk in Patients with Osteolytic Periacetabular Metastases".

The Journal of bone and joint surgery. American volume·2026
Same journal

Can We Find the Oracle of Fracture Union?: Commentary on an article by Luke A. Lopas, MD, et al.: "A Fracture Healing Odyssey: Kinematic Comparison of Unions and Nonunions in Human Lower-Extremity Long Bones Treated with Intramedullary Nailing. A Retrospective Cohort Study".

The Journal of bone and joint surgery. American volume·2026
Same journal

Stacked-Cone Constructs for Extensive Tibial and/or Femoral Bone Loss in Complex Primary and Revision TKA: A Multicenter Analysis of 84 Cases.

The Journal of bone and joint surgery. American volume·2026
Same journal

Shaping Modern Practice in South Korea: A Centennial Review of Orthopaedics at Severance Hospital and Yonsei University College of Medicine.

The Journal of bone and joint surgery. American volume·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

A sixty-five-year-old man with a right total knee replacement experienced recurrent knee sepsis and cachexia. Despite multiple treatments, the infection persisted, leading to the recommendation for component removal.

Area of Science:

  • Orthopaedic Surgery
  • Infectious Disease
  • Medical Ethics

Background:

  • A patient with a history of right total knee replacement presented with recurrent sepsis.
  • Initial treatment involved arthroscopic debridement and intravenous antibiotics, but the patient left against medical advice.

Observation:

  • The patient presented with severe knee infection (80,000 WBC/mm³), cachexia, and altered mental status.
  • Diagnostic workup for metastatic disease and occult neoplasm was negative.
  • Psychiatric evaluations determined decisional incapacity, later reversed at a skilled-nursing facility.

Findings:

  • Despite surgical debridement and antibiotics, the knee infection persisted.
  • The patient refused recommended surgical intervention (component removal) due to a desire to retain the knee replacement.
Keywords:
Professional Patient Relationship

Related Experiment Videos

  • The medical team concluded that infection control was not feasible with the components in place.
  • Implications:

    • This case highlights challenges in managing persistent periprosthetic joint infections, especially with patient non-compliance.
    • Decisional capacity and patient preferences significantly impact treatment pathways for complex orthopaedic infections.
    • Effective management requires a multidisciplinary approach, addressing both infectious and psychosocial aspects.