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The use of solid-phase microextraction--gas chromatography in forensic analysis.
1Department of Chemistry and the International Forensic Research Institute, Florida International University, Miami 33199, USA.
Journal of Chromatographic Science
|July 20, 2000
Summary
Solid-phase microextraction (SPME) offers a rapid, sensitive, and cost-effective method for analyzing diverse forensic samples. This review highlights its application in identifying accelerants, explosives, drugs, and poisons in various specimens.
Area of Science:
- Forensic Science
- Analytical Chemistry
- Chromatography
Background:
- Solid-phase microextraction (SPME) is a versatile technique for sample preparation.
- Gas chromatography (GC) is a standard method for analyzing volatile and semi-volatile compounds.
Purpose of the Study:
- To comprehensively review the application of SPME-GC in forensic specimen analysis.
- To present recent experimental results and novel SPME methods in forensics.
Main Methods:
- Solid-phase microextraction (SPME) coupled with gas chromatography (GC).
- Analysis of various forensic matrices including biological specimens, ignitable liquid residues, and explosive traces.
Main Results:
- SPME-GC effectively analyzes ignitable liquid residues, explosives, drugs, and poisons.
- New SPME methods enable analysis of skin-residue accelerants, odor signatures, and drug levels without derivatization.
Conclusions:
- SPME-GC is an inexpensive, rapid, and sensitive technique for a wide range of forensic analyses.
- SPME-GC is a valuable tool for advancing forensic science capabilities.