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Lipid analog with 2-nitrophenol trigger designed for liposome fusion at physiological pH
S N Shah1, T Tomohiro, Y Ogawa
1Biomolecules Department, National Institute of Bioscience and Human-Technology, Tsukuba, Ibaraki, Japan.
Lipids
|July 20, 2000
Abstract:
A novel lipid analog with two long alkyl (C16) chains, an aspartate skeleton, a connecting alkyl (C8) chain, and 2-nitrophenol trigger group is synthesized by an efficient synthetic route, which can induce liposome fusion at physiological pH.