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Generalized lichen amyloidosis associated with chronic lichen planus
W Hongcharu1, M Baldassano, E Gonzalez
1Department of Dermatology, Harvard Medical School, Dermatology Service, Massachusetts General Hospital, Boston, MA, USA.
Journal of the American Academy of Dermatology
|July 20, 2000
Summary
This report details the first known case of lichen amyloidosis developing in a patient with chronic lichen planus. The study discusses how both conditions responded differently to etretinate treatment.
Area of Science:
- Dermatology
- Pathology
Background:
- Chronic lichen planus is an inflammatory condition affecting the skin.
- Lichen amyloidosis is a distinct condition characterized by amyloid deposition.
Observation:
- A patient with a history of chronic lichen planus developed lichen amyloidosis.
- This represents the first documented instance of these two conditions coexisting in a single patient.
Findings:
- The patient exhibited a disparate response to etretinate therapy.
- Lichen planus and lichen amyloidosis showed differential sensitivity to the treatment.
Implications:
- This case highlights the potential for lichen amyloidosis to develop in patients with chronic lichen planus.
- Understanding the differential response to treatments like etretinate is crucial for managing coexisting dermatoses.