Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Response to IgE].

J M Tunon de Lara1, A Magnan, M Humbert

  • 1Service des Maladies Respiratoires, INSERM E9937, CHU, Bordeaux.

Revue Des Maladies Respiratoires
|July 21, 2000
PubMed
Summary
This summary is machine-generated.

The immunoglobulin E (IgE) response is central to allergic diseases, involving antibody interactions with cell receptors that drive inflammation. Understanding IgE regulation and its dysregulation is key to developing effective treatments for atopic conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beyond the shunt: Divergent insights from hyperoxia testing and contrast echocardiography in adults with pulmonary hypertension.

Physiological reports·2025
Same author

Return to work, after head and neck cancer: results from the French VICAN study.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2025
Same author

Combined multimodal therapy in high-risk patients with chronic thromboembolic pulmonary hypertension and both distal and proximal lesions: A prospective observational cohort study.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2025
Same author

Social health at 5 years after diagnosis of head and neck cancer.

Oral oncology·2025
Same author

Optimal approach to performing and reporting computed tomography angiography for suspected acute pulmonary embolism: a clinical consensus statement of the ESC Working Group on Pulmonary Circulation & Right Ventricular Function, the Fleischner Society, the Association for Acute CardioVascular Care (ACVC) and the European Association of Cardiovascular Imaging (EACVI) of the ESC, endorsed by European Respiratory Society (ERS), Asian Society of Thoracic Radiology (ASTR), European Society of Thoracic Imaging (ESTI), and Society of Thoracic Radiology (STR).

European heart journal. Cardiovascular Imaging·2025
Same author

[Impact of Rac1 activation on eosinophil degranulation in severe asthma].

Revue des maladies respiratoires·2025
Same journal

[French version of the guidelines for connective tissue disease-associated ILD].

Revue des maladies respiratoires·2026
Same journal

[Pulmonary expression of an asymptomatic lysosomal storage disorder].

Revue des maladies respiratoires·2026
Same journal

[Factors associated with FEV1 evolution in cystic fibrosis patients treated by CFTR modulator tritherapy].

Revue des maladies respiratoires·2026
Same journal

[Subacute pulmonary coccidioidomycosis: A differential diagnosis of lung cancer].

Revue des maladies respiratoires·2026
Same journal

[Relevance of the ACT score in severe asthma with obesity: A pilot study].

Revue des maladies respiratoires·2026
Same journal

[Automated analysis of mandibular movements for the screening of obstructive sleep apnea].

Revue des maladies respiratoires·2026
See all related articles

Area of Science:

  • Immunology
  • Allergy Research
  • Molecular Biology

Context:

  • The immunoglobulin E (IgE) antibody response is implicated in allergic diseases.
  • IgE antibodies mediate immediate hypersensitivity reactions by binding to specific receptors on cell surfaces.
  • Activation of these receptors contributes to allergic inflammation.

Purpose:

  • To explore the complex regulation of the IgE response.
  • To understand the role of factors modulating IgE isotype synthesis, FcERII:CD23, and the Th1/Th2 balance.
  • To examine the link between IgE dysregulation and Th2-biased immune responses in allergic diseases.

Summary:

  • The IgE response, crucial in allergic diseases, involves antibodies binding to cell receptors, triggering inflammation.
  • Complex regulatory mechanisms, including FcERII:CD23 and Th1/Th2 balance, control IgE synthesis.

Related Experiment Videos

  • Allergic diseases feature a dysregulated IgE response, often linked to a Th2-dominant imbalance.

    • Impact:

    • Advances in anti-IgE therapies offer new avenues for managing atopic diseases.
    • Further research into the IgE response's role in inflammation will refine treatment strategies.
    • Elucidating IgE's precise role is vital for improving allergic disease management.