Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Compound acquisition strategies.

J B Dunbar1

  • 1Parke Davis Pharmaceutical Research Division, Warner Lambert Company, Ann Arbor, Michigan 48015, USA.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
|July 21, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mortality among US commercial pilots and navigators.

Journal of occupational and environmental medicine·1998
Same author

Cosmic radiation and magnetic field exposure to airline flight crews.

American journal of industrial medicine·1998
Same author

X-ray structure of a hydroxamate inhibitor complex of stromelysin catalytic domain and its comparison with members of the zinc metalloproteinase superfamily.

Structure (London, England : 1993)·1996
Same author

Designing inhibitors of the metalloproteinase superfamily: comparative analysis of representative structures.

Drug design and discovery·1996
Same author

Enhancing the diversity of a corporate database using chemical database clustering and analysis.

Journal of computer-aided molecular design·1995
Same author

Characterization of endothelins as chemoattractants for human neutrophils.

Life sciences·1994
Same journal

Trust, Reproducibility, and Progress: The Roles of Independent Blind Prediction and Assessment and Benchmarking in Computational Biology.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing·2026
Same journal

The Evolving Cyberinfrastructure at the National Institutes of Health to Support Data and AI in Biomedical Research.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing·2026
Same journal

Applications of AI & ML in Biomanufacturing of Cell and Gene Therapies.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing·2026
Same journal

AI for Health: Leveraging Artificial Intelligence to Revolutionize Healthcare.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing·2026
Same journal

Workshop Introduction: Advances of AI Methods in Single Cell Spatial Omics.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing·2026
Same journal

DRIVE-KG: Enhancing variant-phenotype association discovery in understudied complex diseases using heterogeneous knowledge graphs.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing·2026
See all related articles

Efficient compound acquisition is crucial for discovering new biologically active compounds. This presentation covers key techniques and processes for optimizing compound screening in drug discovery.

Area of Science:

  • Medicinal Chemistry
  • Drug Discovery
  • Chemical Biology

Background:

  • Compound acquisition is vital for identifying novel biologically active molecules.
  • High-throughput screening (HTS) demands a large number of high-quality compounds.
  • Accelerated drug discovery timelines necessitate efficient acquisition strategies.

Purpose of the Study:

  • To discuss techniques and processes for effective compound acquisition.
  • To highlight the importance of compound quality and quantity in HTS.
  • To provide insights into optimizing the compound acquisition pipeline.

Main Methods:

  • Review of current compound acquisition strategies.
  • Analysis of process optimization in compound sourcing.
  • Discussion of quality control measures for screening libraries.

Related Experiment Videos

Main Results:

  • Identification of key factors influencing successful compound acquisition.
  • Evaluation of different approaches for library expansion.
  • Emphasis on the balance between compound diversity and quality.

Conclusions:

  • Optimized compound acquisition accelerates the identification of drug leads.
  • Strategic sourcing and quality control are paramount for HTS success.
  • Technological advancements continue to enhance compound acquisition efficiency.