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ALFRED: a Web-accessible allele frequency database.

K H Cheung1, P L Miller, J R Kidd

  • 1Center for Medical Informatics, Yale University School of Medicine, New Haven, CT 06520-8009, USA. kei.cheung@yale.edu

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
|July 21, 2000
PubMed
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ALFRED provides public access to a comprehensive gene frequency database, offering population-specific allele frequency estimates for over 150 genetic systems across 40+ global populations. This resource aids researchers needing detailed genetic data.

Area of Science:

  • Population Genetics
  • Bioinformatics
  • Genomics

Background:

  • Accurate population-specific gene frequency data is crucial for genetic research.
  • Existing resources may not adequately meet the diverse needs of the scientific community for detailed genetic information.

Purpose of the Study:

  • To introduce ALFRED, a web-accessible database for public access to gene frequency data.
  • To provide population-specific allele frequency estimates for a wide range of genetic systems.
  • To meet the needs of the scientific community for comprehensive genetic data.

Main Methods:

  • Development of a web-accessible database (ALFRED).
  • Inclusion of data on over 40 populations globally.
  • Incorporation of data for more than 150 genetic systems, including SNPs, STRPs, and insertion-deletion polymorphisms.

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Main Results:

  • ALFRED contains data for over 40 populations and 150 genetic systems.
  • Over 2000 allele frequency tables are currently available.
  • The database is designed to meet broad scientific needs for population-specific gene frequency estimates.

Conclusions:

  • ALFRED serves as a valuable public resource for population genetic data.
  • The database facilitates research requiring precise allele frequency information.
  • ALFRED complements existing databases like dbSNP by offering specialized population genetic data.