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Related Experiment Videos

[Intrahepatic cholestasis induced by amoxicillin alone].

H Bolzan1, J Spatola, R Castelletto

  • 1Servicio de Gastroenterología, Hospital Municipal de Lincoln, La Plata, República Argentina.

Gastroenterologia Y Hepatologia
|July 21, 2000
PubMed
Summary

A rare case of acute cholestasis was linked to amoxicillin, a common antibiotic. Prompt withdrawal of amoxicillin led to patient recovery, highlighting this potential drug-induced liver injury.

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Area of Science:

  • Hepatology
  • Clinical Pharmacology
  • Internal Medicine

Background:

  • Acute cholestasis presents with impaired bile flow, leading to jaundice and abnormal liver function tests.
  • Drug-induced liver injury (DILI) is a significant cause of liver disease, with antibiotics being common culprits.
  • Amoxicillin, a widely used antibiotic, is rarely associated with cholestatic liver injury.