Related Experiment Video
Updated: Aug 2, 2026

14:20
High Throughput SiRNA Screening for Chloropicrin and Hydrogen Fluoride-Induced Cornea Epithelial Cell Injury
Published on: June 16, 2018
Chemical sensitivity and gulf war veterans' illnesses
1Boston Environmental Hazards Center, Boston University, Boston, MA, USA.
Summary
Gulf War veterans experience significant rates of chemical sensitivity (CS) and multiple chemical sensitivity (MCS) syndrome. Further research is crucial to understand and address these health concerns in veterans.
Area of Science:
- Environmental Health
- Veterans' Health
- Toxicology
Background:
- Gulf War veterans report a high prevalence of health issues.
- Chemical sensitivity (CS) and multiple chemical sensitivity (MCS) syndrome are key concerns.
- Existing research uses varied criteria and measures for CS and MCS.
Purpose of the Study:
- To summarize current research on Gulf War veterans' health, focusing on CS and MCS.
- To highlight the prevalence rates of CS and MCS in this population.
- To identify the need for targeted research.
Main Methods:
- Literature review of studies on Gulf War veterans' health.
- Analysis of reported prevalence rates for CS and MCS.
- Examination of differing assessment criteria and measures.
Main Results:
- CS prevalence in Department of Veterans' Affairs populations: 36-86%.
- CS prevalence in general Gulf War veteran cohorts: 0.8-20%.
- MCS prevalence: 2-6%.
Conclusions:
- Gulf War veterans exhibit notable rates of CS and MCS.
- Variability in study criteria complicates direct comparisons.
- Targeted research is essential for adequate evaluation of veterans' health concerns and MCS.
Related Concept Videos
Toxic Reactions: Overview
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Toxicity Testing in Animals
Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
Giardiasis
Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...

