Related Experiment Videos
Colchicine-induced myopathy in renal failure
S Sinsawaiwong1, K Phanthumchinda, S Jongpiputvanich
1Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Summary
Colchicine can cause myopathy, especially in patients with chronic renal failure. Discontinuation of colchicine led to muscle improvement, suggesting cautious use in patients with kidney impairment.
Area of Science:
- Nephrology
- Neurology
- Toxicology
Background:
- Colchicine is a common medication for gout and familial Mediterranean fever.
- Chronic renal failure (CRF) affects drug metabolism and excretion.
- Drug-induced myopathy is a potential adverse effect of various medications.