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Related Experiment Videos

The acrodermatitis enteropathica-like syndrome.

S A Brazin, W T Johnson, L J Abramson

    Archives of Dermatology
    |May 1, 1979
    PubMed
    Summary

    Severe bowel disease and zinc deficiency from hyperalimentation can cause an acrodermatitis enteropathica-like syndrome. Early and sufficient zinc replacement is crucial for preventing or reversing this condition.

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    Area of Science:

    • Dermatology
    • Nutritional Science
    • Gastroenterology

    Background:

    • Severe intestinal diseases can impair nutrient absorption.
    • Intravenous feeding (hyperalimentation) regimens may lead to specific nutrient deficiencies if not properly managed.
    • Zinc is an essential trace element vital for skin health and immune function.

    Observation:

    • A case study identified an acrodermatitis enteropathica-like syndrome.
    • This syndrome was linked to underlying severe bowel disease.
    • The condition was exacerbated by zinc-deficient hyperalimentation.

    Findings:

    • The syndrome presented with skin lesions characteristic of zinc deficiency.
    • Laboratory tests confirmed low serum zinc levels.
    • The clinical presentation mimicked the genetic disorder acrodermatitis enteropathica.

    Implications:

    • Early diagnosis and intervention are critical for managing this iatrogenic condition.
    • Adequate zinc supplementation is essential for patients with severe bowel disease on hyperalimentation.
    • Prompt zinc replacement can effectively reverse the dermatological and potentially systemic effects.

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