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Recurrent cholestatic jaundice associated with generalized pustular psoriasis: evidence for a neutrophilic
M Allez1, M E Roux, P Bertheau
1Service d'Hépato-Gastroentérologie, Hôpital Saint-Louis, Paris, France. allez.matthieu@chu-stlouis.fr
Journal of Hepatology
|July 25, 2000
Abstract:
Generalized pustular psoriasis can result in systemic complications. We report the case of a woman with relapsing generalized pustular psoriasis and recurring episodes of cholestatic jaundice. Liver biopsy performed during an attack showed a neutrophilic infiltrate surrounding and invading portal triad bile ducts. Ultrasonographic exams and retrograde cholangiography ruled out biliary tract disease. This observation suggests that recurring cholestatic jaundice in pustular psoriasis is related to a neutrophilic cholangitis.