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Updated: Jul 21, 2026
Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
High-resolution transmission electron microscopy investigations of a highly adhesive hydroxyapatite coating/titanium
1Beijing Laboratory of Electron Microscopy, Institute of Physics and Center for Condensed Matter Physics, Chinese Academy of Sciences, P. O. Box 2724, Beijing 100080, China.
Abstract:
An atomic intermixing layer, 25 nm in width, has been identified by high-resolution transmission electron microscopy (HRTEM) and energy-dispersive X-ray spectroscopy (EDS) analysis at the ceramic/metal interface of a hydroxyapatite (HA) coating/titanium implant prepared by an ion-beam-assisted deposition (IBAD) technique and post-heat-treatment process. The detailed interfacial microstructure revealed a gradient evolution of both the structure and composition of the interfacial phases from the titanium substrate to HA coatings. An enhancement of the tensile bond strength was found and was attributed to the possible chemical bonding at the ceramic/metal interface.
