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A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo
Published on: August 28, 2014
Treatment of soft tissue defects in pediatric patients using the V.A.C. system
J F Mooney1, L C Argenta, M W Marks
1Department of Pediatric Orthopaedic Surgery, Wayne State University School of Medicine, Detroit, MI, USA.
Insights
The Vacuum Assisted Closure (V.A.C.) system effectively heals complex pediatric soft tissue wounds. This innovative vacuum therapy promotes granulation tissue, reducing the need for extensive reconstructive surgery.
Area of Science:
- Orthopaedic Surgery
- Plastic Surgery
- Wound Healing
Background:
- Pediatric patients with complex soft tissue wounds often require extensive coverage procedures.
- Previous treatments for such wounds included surgical closure, flaps, and free tissue transfer.
Observation:
- Twenty-seven pediatric patients with complex soft tissue wounds were treated with the Vacuum Assisted Closure (V.A.C.) system.
- The V.A.C. system was used for acute wounds and those resulting from failed surgical closures.
Findings:
- All soft tissue defects healed without extensive coverage procedures.
- The V.A.C. system promoted granulation tissue formation, enabling coverage with skin grafts or local flaps.
- Healing was achieved through delayed primary closure, local flap advancement, or secondary intention.
Implications:
- The V.A.C. system accelerates healing and granulation tissue formation in pediatric patients.
- It reduces the need for microvascular tissue transfers, offering a less invasive approach.
- This technology improves outcomes for extensive soft tissue injuries in children.
Abstract:
Twenty-seven consecutive pediatric patients presenting to the orthopaedic surgery or plastic surgery services were reviewed after completion of wound care with the Vacuum Assisted Closure (V.A.C.) system. Each patient presented with complex soft tissue wounds requiring coverage procedures. Patients with acute wounds and wounds present after nonsuccessful attempts at surgical closure (dehisced incisions and failed flaps) were treated. All soft tissue defects healed without extensive coverage procedures using the V.A.C. system. In the majority of patients, use of the V.A.C. system produced a profuse bed of granulation tissue over all exposed bone, tendon, joint, and/or hardware, which could be covered with split thickness skin graft. Other patients were treated successfully with delayed primary closure, local flap advancement (one patient underwent a pedicled cross-leg flap), or by secondary intention. Use of the V.A.C. device is valuable in increasing the rate of granulation tissue formation and healing of extensive soft tissue injuries in pediatric patients. This vacuum system aids in the debridement of necrotic tissue and local soluble inflammatory mediators that may inhibit the proliferation of granulation tissue. These improvements in the local wound environment seem to accelerate wound healing compared with traditional methods. Before the development of the V.A.C. system, a minimum of nine patients within this group would have required free tissue transfer to obtain adequate coverage. The V.A.C. device seems to permit earlier coverage with local tissue or split-thickness skin grafting techniques, thereby decreasing the need for extensive microvascular tissue transfers in pediatric patients.
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