Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stuttering: an update for physicians.

D Costa1, R Kroll

  • 1Speech Foundation of Ontario Stuttering Centre, Toronto. dcosta3@attglobal.net

CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne
|July 25, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence of anterior uveitis in dogs diagnosed with pyometra.

The Journal of small animal practice·2025
Same author

Current knowledge and practice of Candida auris screening in France: A nationwide survey from the French Society of Medical Mycology (SFMM).

Journal de mycologie medicale·2024
Same author

Role of IL33 in chronic inflammation and microvascular damage as a reflection of organ damage on a cohort of patients with acromegaly.

Journal of endocrinological investigation·2024
Same author

Impact of the physical properties of contact lens materials on the discomfort: role of the coefficient of friction.

Colloids and surfaces. B, Biointerfaces·2023
Same author

Erectile function and androgen and estrogen beta receptor gene polymorphisms in acromegalic men.

Journal of endocrinological investigation·2023
Same author

Multicentric Analysis of the Species Distribution and Antifungal Susceptibility of Clinical Isolates from Aspergillus Section <i>Circumdati</i>.

Antimicrobial agents and chemotherapy·2023
Same journal

Rheumatoid synovitis of the elbow mimicking rheumatoid nodule.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2026
Same journal

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2026
Same journal

What pool closures in Canada mean for health.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2026
Same journal

Fatal rabies in a child.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2026
Same journal

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2026
Same journal

Otitis externa.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2026
See all related articles

Developmental stuttering (DS) is a speech disorder often starting in childhood. Research suggests a hyperdopaminergic origin, with treatments like speech therapy and certain medications showing promise.

Area of Science:

  • Neuroscience
  • Speech and Language Pathology

Background:

  • Developmental stuttering (DS) is a common speech disorder characterized by disruptions in fluency and timing.
  • Persistent developmental stuttering (PDS) refers to DS that does not resolve spontaneously or with therapy.
  • Potential causes include genetic factors, abnormal cerebral dominance, and a hyperdopaminergic origin.

Purpose of the Study:

  • To review the current understanding of developmental stuttering.
  • To explore the neurobiological underpinnings and treatment options for DS.

Main Methods:

  • Review of neuroimaging research.
  • Analysis of clinical trial data for pharmacological interventions.
  • Evaluation of speech therapy outcomes.

Related Experiment Videos

Main Results:

  • Neuroimaging and pharmacological evidence support a hyperdopaminergic hypothesis for DS.
  • Speech therapy is the primary treatment.
  • Antidepressants and serotonin-dopamine antagonists like risperidone show potential benefits.

Conclusions:

  • Developmental stuttering has complex origins, potentially involving genetic and neurobiological factors.
  • Pharmacological interventions, particularly serotonin-dopamine antagonists, warrant further investigation for long-term efficacy and safety in DS treatment.