[Hormonal replacement therapy and body weight in postmenopausal women]

Prospective studies that included 116 postmenopausal women on hormonal replacement therapy (transdermal estradiol and medroxyprogesterone acetate orally) was performed. Body mass index (BMI), total cholesterol concentration, levels of HDL and LDL-cholesterol were measured before and after 6 and 12 months of continuous treatment. Body mass index revealed no changes during one year of therapy. HDL-cholesterol significantly increased (p < 0.05) and LDL-cholesterol was significantly decreased after 6 and 12 months of HRT.