[Hormonal replacement therapy and body weight in postmenopausal women]
Related Experiment Video
Updated: Oct 15, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
1Oddziału Ginekologii i Połoznictwa Szpitala Miejskiego w Gdyni.
Abstract:
Prospective studies that included 116 postmenopausal women on hormonal replacement therapy (transdermal estradiol and medroxyprogesterone acetate orally) was performed. Body mass index (BMI), total cholesterol concentration, levels of HDL and LDL-cholesterol were measured before and after 6 and 12 months of continuous treatment. Body mass index revealed no changes during one year of therapy. HDL-cholesterol significantly increased (p < 0.05) and LDL-cholesterol was significantly decreased after 6 and 12 months of HRT.
Related Concept Videos
Menopause
Bone Remodeling
Hormonal Control of the Ovarian Cycle
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Hormonal Regulation
Hormonal Regulation