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[The spectrum of cytotoxic lymphomas of the skin]
L el Shabrawi-Caelen1, L Cerroni, W Sterry
1Universitätsklinik für Dermatologie und Venerologie Graz.
Abstract:
Cytotoxic lymphomas are peripheral T- and natural killer-cell lymphomas with primary or secondary skin manifestations. They constitute a heterogeneous group of lymphoproliferative disease. They are characterized by expression of cytotoxic proteins and are frequently associated with an aggressive clinical course. A brief introduction to cytotoxic lymphocytes and proteins is followed by a detailed description of clinical, histological, immunohistochemical and genetic characteristics of cutaneous cytotoxic lymphomas.
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