Arsenicals and inhibitors of histone deacetylase as anticancer therapy

Acute promyelocytic leukemia cell line AP-1060 established as a cytokine-dependent culture from a patient clinically resistant to all-trans retinoic acid and arsenic trioxide.

Leukemia·2004

Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia.

The Journal of clinical investigation·2001

Prognostic significance of minimal residual disease detection and PML/RAR-alpha isoform type: long-term follow-up in acute promyelocytic leukemia.

Blood·2001

United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2001

Differentiating agents in pediatric malignancies: all-trans-retinoic acid and arsenic in acute promyelocytic leukemia.

Current oncology reports·2000

Inhaled aerosolization of all-trans-retinoic acid for targeted pulmonary delivery.

Cancer chemotherapy and pharmacology·2000

Autoimmune and inflammatory diseases associated with T-cell clonal expansion.

Haematologica·2026

Macrophage-specific LAMTOR2 deletion disrupts systemic iron homeostasis in mice.

Haematologica·2026

Dual inhibition of JAK and MEK suppresses T-cell acute lymphoblastic leukemia induced by mutant IL7R and RASGRP1 overexpression.

Haematologica·2026

Validation of the International Working Group 2023 response criteria for higher risk myelodysplastic syndromes/neoplasms using the International Consortium for Myelodysplastic Syndromes VALIDATE database and a randomized phase III trial.

Haematologica·2026

Preserving anthracycline-containing treatment in older patients with classical Hodgkin lymphoma: a role for liposomal doxorubicin. Comment on: "Age, anthracycline and mortality in 28,000 classic Hodgkin lymphoma patients: cohort study of a complete population".

Haematologica·2026

Mesenchymal stem cells in ribosomal insufficiency lead to aberrant osteoblastic differentiation and altered hematopoiesis.

Haematologica·2026

An old ligand learns a new trick: 2,9-di(pyrid-2-yl)-1,10-phenanthroline discriminates PFOA from PFOS in water.

Chemical communications (Cambridge, England)·2026

Structural basis for ITP-selective hydrolysis by a CRISPR-associated Nudix hydrolase.

Journal of bacteriology·2026

RETRACTED: Abdullah, M.M.S.; Al-Lohedan, H.A. Novel Bio-Based Amphiphilic Ionic Liquids for the Efficient Demulsification of Heavy Crude Oil Emulsions. Molecules 2021, 26, 6119.

Molecules (Basel, Switzerland)·2026

Related Experiment Videos

Arsenicals and inhibitors of histone deacetylase as anticancer therapy

Related Concept Videos

Acute promyelocytic leukemia cell line AP-1060 established as a cytokine-dependent culture from a patient clinically resistant to all-trans retinoic acid and arsenic trioxide.

Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia.

Prognostic significance of minimal residual disease detection and PML/RAR-alpha isoform type: long-term follow-up in acute promyelocytic leukemia.

United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia.

Differentiating agents in pediatric malignancies: all-trans-retinoic acid and arsenic in acute promyelocytic leukemia.

Inhaled aerosolization of all-trans-retinoic acid for targeted pulmonary delivery.

Autoimmune and inflammatory diseases associated with T-cell clonal expansion.

Macrophage-specific LAMTOR2 deletion disrupts systemic iron homeostasis in mice.

Dual inhibition of JAK and MEK suppresses T-cell acute lymphoblastic leukemia induced by mutant IL7R and RASGRP1 overexpression.

Validation of the International Working Group 2023 response criteria for higher risk myelodysplastic syndromes/neoplasms using the International Consortium for Myelodysplastic Syndromes VALIDATE database and a randomized phase III trial.

Preserving anthracycline-containing treatment in older patients with classical Hodgkin lymphoma: a role for liposomal doxorubicin. Comment on: "Age, anthracycline and mortality in 28,000 classic Hodgkin lymphoma patients: cohort study of a complete population".

Mesenchymal stem cells in ribosomal insufficiency lead to aberrant osteoblastic differentiation and altered hematopoiesis.

An old ligand learns a new trick: 2,9-di(pyrid-2-yl)-1,10-phenanthroline discriminates PFOA from PFOS in water.

Structural basis for ITP-selective hydrolysis by a CRISPR-associated Nudix hydrolase.

RETRACTED: Abdullah, M.M.S.; Al-Lohedan, H.A. Novel Bio-Based Amphiphilic Ionic Liquids for the Efficient Demulsification of Heavy Crude Oil Emulsions. Molecules 2021, 26, 6119.

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Arsenicals and inhibitors of histone deacetylase as anticancer therapy

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