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Does asphyxia cause cerebral palsy?

E R Pschirrer1, E R Yeomans

  • 1Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Texas-Houston Medical School, USA.

Seminars in Perinatology
|July 25, 2000
PubMed
Summary

Perinatal asphyxia causes a small fraction of cerebral palsy cases. Severe fetal academia is the key factor linking asphyxia to cerebral palsy and neonatal encephalopathy.

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Area of Science:

  • Neurology
  • Neonatal Medicine
  • Pediatric Neurology

Background:

  • Cerebral palsy affects 1 in 1,000 individuals.
  • Perinatal asphyxia is implicated in only 8-10% of cerebral palsy cases.

Purpose of the Study:

  • To review the scientific literature on the relationship between perinatal asphyxia and cerebral palsy.
  • To identify the specific conditions under which asphyxia increases the risk of cerebral palsy.

Main Methods:

  • Literature review of studies investigating perinatal asphyxia and cerebral palsy.
  • Analysis of cases involving neonatal encephalopathy and severe pathological fetal academia.

Main Results:

  • A minority of cerebral palsy cases are linked to perinatal asphyxia.
  • Severe pathological fetal academia is consistently associated with neonatal encephalopathy.
  • Neonatal encephalopathy due to severe pathological fetal academia increases cerebral palsy risk.

Conclusions:

  • Perinatal asphyxia is not a common cause of cerebral palsy.
  • Severe pathological fetal academia is a critical determinant in the asphyxia-cerebral palsy link.
  • Targeting interventions for severe fetal academia may mitigate cerebral palsy risk.

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