Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interventions for treating scabies.

G J Walker1, P W Johnstone

  • 1Country Support Team for Central and South Asia, UNFPA, PO Box 5940, Kathmandu, Nepal. gwalker@unfpa.wlink.com.np

The Cochrane Database of Systematic Reviews
|July 25, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Faecal calprotectin effectively excludes inflammatory bowel disease in 789 symptomatic young adults with/without alarm symptoms: a prospective UK primary care cohort study.

Alimentary pharmacology & therapeutics·2018
Same author

Melanocyte transformation requires complete loss of all pocket protein function via a mechanism that mitigates the need for MAPK pathway activation.

Oncogene·2017
Same author

Bis: looking beyond the number.

British journal of anaesthesia·2016
Same author

Murine melanomas accelerated by a single UVR exposure carry photoproduct footprints but lack UV signature C>T mutations in critical genes.

Oncogene·2015
Same author

Melanoma susceptibility as a complex trait: genetic variation controls all stages of tumor progression.

Oncogene·2014
Same author

No effect of fluid intake on neutrophil responses to prolonged cycling.

Journal of sports sciences·2005
Same journal

Interventions to prevent or cease electronic cigarette use in children and adolescents.

The Cochrane database of systematic reviews·2026
Same journal

Drugs to improve anaemia, quality of life, and physical function in people with myelodysplastic syndromes (MDS).

The Cochrane database of systematic reviews·2026
Same journal

Interventions for smoking cessation in inpatient psychiatry settings.

The Cochrane database of systematic reviews·2026
Same journal

Mechanical thromboprophylaxis for preventing intradialytic hypotension in people undergoing maintenance haemodialysis.

The Cochrane database of systematic reviews·2026
Same journal

Prognostic models for predicting intensive care unit admission or mortality in critically ill adults not yet been admitted to the intensive care unit.

The Cochrane database of systematic reviews·2026
Same journal

Views and experiences of weight management for people living with mobility‑limiting conditions, intellectual disabilities or severe mental illness: a qualitative evidence synthesis.

The Cochrane database of systematic reviews·2026
See all related articles

Scabies treatment effectiveness varies. Permethrin may be more effective than crotamiton, but evidence comparing it to lindane is inconsistent. Serious adverse reactions to scabicides like lindane, permethrin, and ivermectin are reported.

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Pharmacology

Background:

  • Scabies is a widespread parasitic skin infestation affecting 300 million globally.
  • It causes significant discomfort, intense itching, and potential severe adverse drug effects.
  • Current treatments require careful consideration of efficacy and toxicity.

Purpose of the Study:

  • To systematically review the efficacy and toxicity of various topical and systemic drugs for scabies treatment.
  • To synthesize evidence from randomized controlled trials on scabies pharmacotherapy.
  • To identify gaps in research regarding scabies treatment options.

Main Methods:

  • Comprehensive literature search across multiple databases (Cochrane, MEDLINE, EMBASE) and other sources.
  • Inclusion of randomized controlled trials evaluating drug treatments for scabies.

Related Experiment Videos

  • Assessment of trial quality and data extraction by independent reviewers.

    • Main Results:

    • Permethrin showed potential for higher cure rates than crotamiton and possibly lindane, though evidence is inconsistent.
    • Ivermectin demonstrated a higher clinical cure rate than placebo in one small trial.
    • Serious adverse drug reactions, particularly with lindane, permethrin, and ivermectin, have been documented in non-trial data.

    Conclusions:

    • Evidence for permethrin's superiority over lindane is inconsistent.
    • Lindane, permethrin, and ivermectin are associated with rare but serious adverse reactions.
    • Further research is crucial for ivermectin, malathion, community management, and topical treatment variations.