Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Analysis of prostate seed loading for permanent implants.

C C Lamb1, P Meskell, E J Holupka

  • 1Joint Center for Radiation Therapy, Harvard Medical School, Boston, Massachusetts, USA. clamb@caregroup.harvard.edu

Journal of Endourology
|July 26, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a Core Outcome Set for research studies with older adults in the Emergency Department-CREAT-ED: A multi-stage study protocol.

Trials·2026
Same author

Patients', family members' and healthcare practitioners' experiences of Stevens-Johnson syndrome and toxic epidermal necrolysis: a qualitative descriptive study using emotional touchpoints.

Journal of the European Academy of Dermatology and Venereology : JEADV·2020
Same author

The psychological impact of Stevens-Johnson syndrome and toxic epidermal necrolysis on patients' lives: a Critically Appraised Topic.

The British journal of dermatology·2019
Same author

High risk HPV testing following treatment for cervical intraepithelial neoplasia.

Irish journal of medical science·2015
Same author

Challenges to quality testing for bovine tuberculosis in Ireland; perspectives from major stakeholders.

The Veterinary record·2013
Same author

An automatic seed finder for brachytherapy CT postplans based on the Hough transform.

Medical physics·2004
Same journal

Is Nonpapillary Puncture a Feasible Alternative to Papillary Access in Percutaneous Nephrolithotomy? A Systematic Review and Meta-Analysis.

Journal of endourology·2026
Same journal

Procedure, Safety, and Outcomes of Patient-Controlled Sedation in Ureteroscopic Lithotripsy: A 7-Year Cohort Study.

Journal of endourology·2026
Same journal

Clinically Significant Prostate Cancer in Patients Undergoing Holmium Laser Enucleation of Prostate for Benign Hyperplasia: A Preoperative Nomogram and a Postoperative Surveillance Protocol.

Journal of endourology·2026
Same journal

Bubble Trouble: The Thermal Risk of Ureteral Laser Lithotripsy in an Air Bubble.

Journal of endourology·2026
Same journal

Development of an Interpretable Machine Learning Model for Predicting Clavien-Dindo Grade ≥2 Complications after Unilateral Minimally Invasive Pyeloplasty in UPJO: A Retrospective Cohort Study.

Journal of endourology·2026
Same journal

Comparison of Appendiceal Onlay Ureteroplasty and Appendiceal Interposition Ureteroplasty for Complex Proximal Ureteral Strictures in Children: Insights Gained from Long-Term Follow-Up.

Journal of endourology·2026
See all related articles

Radioactive seed implantation for prostate cancer now uses 3D planning for custom volume loading. This improves tumor dose uniformity and protects nearby organs like the urethra and rectum.

Area of Science:

  • Oncology
  • Radiation Oncology
  • Medical Physics

Background:

  • Traditional radioactive seed implantation for prostate cancer faced limitations with uniform and peripheral loading techniques.
  • Minimizing radiation dose to adjacent normal tissues while effectively treating the tumor is a primary challenge.

Purpose of the Study:

  • To evaluate the efficacy of custom volume loading using three-dimensional (3D) treatment planning for prostate cancer brachytherapy.
  • To improve dose distribution uniformity and reduce radiation exposure to critical organs.

Main Methods:

  • Utilized volumetric ultrasound imaging for precise gland visualization.
  • Implemented 3D treatment-planning systems for custom seed loading based on individual patient anatomy.
  • Analyzed dose distributions and dosimetry for the prostate tumor and adjacent structures (urethra, rectum).

Related Experiment Videos

Main Results:

  • Custom volume loading resulted in more uniform dose distributions within the prostate gland.
  • Radiation doses to the urethra and rectum were successfully maintained within safe limits.
  • 3D planning enabled personalized treatment strategies for prostate brachytherapy.

Conclusions:

  • Three-dimensional treatment planning and custom volume loading represent a significant advancement in prostate brachytherapy.
  • This approach enhances treatment efficacy by optimizing dose delivery and improves patient safety by sparing critical organs.
  • Volumetric ultrasound-guided custom loading is a superior method compared to older techniques for radioactive seed implantation in prostate cancer.