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Related Experiment Videos

Primary splenic lymphoma in a child.

T H Jaing1, C P Yang

  • 1Department of Pediatric Medicine, Chang Gung Children's Hospital, Taoyuan, Taiwan.

Acta Paediatrica Taiwanica = Taiwan Er Ke Yi Xue Hui Za Zhi
|July 27, 2000
PubMed
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Primary splenic lymphoma, a rare cause of enlarged spleen, was diagnosed in a 10-year-old boy. This case highlights the importance of considering this rare pediatric cancer, with the patient remaining disease-free after treatment.

Area of Science:

  • Pediatric Oncology
  • Hematology
  • Surgical Oncology

Background:

  • Primary splenic lymphoma is an uncommon malignancy, accounting for less than 1% of non-Hodgkin lymphoma cases.
  • Splenomegaly can be caused by various conditions, making the diagnosis of primary splenic lymphoma challenging.

Observation:

  • A 10-year-old boy presented with a large splenic mass discovered incidentally after abdominal trauma.
  • The mass was diagnosed as diffuse large cell lymphoma confined to the spleen.

Findings:

  • Surgical resection followed by adjuvant chemotherapy led to a complete remission.
  • The patient has remained disease-free for 3 years post-diagnosis and treatment.

Implications:

  • This case underscores the importance of considering rare diagnoses like primary splenic lymphoma in pediatric patients with splenomegaly.

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  • Early diagnosis and multimodal treatment, including surgery and chemotherapy, can lead to favorable outcomes in pediatric splenic lymphoma.