Related Experiment Video
Updated: Oct 15, 2026

Invasive Hemodynamic Assessment for the Right Ventricular System and Hypoxia-Induced Pulmonary Arterial Hypertension in Mice
Published on: October 24, 2019
Intraoperative use of inhaled PGI(2) for acute pulmonary hypertension and right ventricular failure
R A Schroeder1, G L Wood, J S Plotkin
1Department of Anesthesia, National Naval Medical Center, Bethesda, Maryland 20889, USA. bekkuo@yahoo.com
Abstract:
Inhaled prostacyclin (PGI(2)) can be used as an effective pulmonary vasodilator intraoperatively to treat pulmonary hypertension and impending right ventricular failure.
Related Concept Videos
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Cardiac Catheterization II: Right Heart Catheterization
Acute Respiratory Failure-IV
