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Peripheral opioid modulation of visceral pain
1Department of Pharmacology, University of Iowa College of Medicine, Iowa City 52242-1109, USA. gf-gebhart@uiowa.edu
Annals of the New York Academy of Sciences
|July 27, 2000
Abstract:
Opioids are widely and successfully used for control of pain, including pain arising from the viscera. Constipating, sedating, respiratory depressant and other effects of opioids, however, often limit their long-term use in the treatment of a variety of visceral pain states. Accordingly, understanding visceral pain mechanisms and its modulation is important to developing improved strategies for pain control.