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Three-dimensional structures of MHC class I-peptide complexes: implications for peptide recognition

K Persson1, G Schneider

  • 1Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

Over the last decade, the number of crystal structures of major histocompatibility complex (MHC) class I-peptide complexes has increased rapidly. These studies have provided unique and fascinating insights into the structural basis of MHC-peptide interactions and the specificity of peptide recognition by MHC class I molecules.

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