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Rapid progressive subacute sclerosing panencephalitis in a 2-year-old child with congenital athyreosis

G M Lackmann1, M Hannen, F Madjlessi

  • 1Department of Pediatrics, Heinrich-Heine University, D-40225 Düsseldorf, Germany.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|July 29, 2000
PubMed

Insights

A young child with congenital athyreosis experienced a rapid, fatal course of subacute sclerosing panencephalitis (SSPE) following concurrent measles and Epstein-Barr virus infections. Early measles infection may have contributed to this aggressive SSPE presentation.

Area of Science:

  • Pediatric Neurology
  • Virology
  • Immunology

Background:

  • Congenital athyreosis is a rare condition affecting thyroid hormone production.
  • Subacute sclerosing panencephalitis (SSPE) is a rare, progressive neurologic complication of measles virus infection.
  • Concurrent viral infections can alter disease presentation and severity.

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