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Taking Advantage of Reduced Droplet-surface Interaction to Optimize Transport of Bioanalytes in Digital Microfluidics
Published on: November 10, 2014
Methods for reducing biosensor membrane biofouling
1Department of Biomedical Engineering, Duke University, 27708, Durham, NC, USA
Colloids and Surfaces. B, Biointerfaces
|August 1, 2000
Abstract:
The deleterious effect that biofouling has on sensor stability is a serious impediment to the development of long term implanted biosensors. This paper reviews the surface modification strategies currently employed to minimize membrane biofouling of in vivo sensors. Nine sensor modifications are discussed herein: hydrogels, phospholipid-based biomimicry, flow-based systems, Nafion, surfactants, naturally derived materials, covalent attachments, diamond-like carbons, and topology.

