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[Hypertensive crisis caused by metoclopramide]
1Ordinacija medicine rada, Zagreb.
Lijecnicki Vjesnik
|August 1, 2000
Abstract:
Metoclopramide is a dopamine-receptor antagonist which stimulates the upper gastrointestinal tract motility. It is often used in the management of some forms of nausea and vomiting. Hypertensive crisis which occurred in a 76-year-old man who had received metoclopramide 30 mg daily is reported.
Insights
Metoclopramide, a dopamine-receptor antagonist, can cause hypertensive crisis. This case report details a 76-year-old man who experienced this adverse event after daily metoclopramide use.
Area of Science:
- Pharmacology
- Gastroenterology
- Clinical Medicine
Background:
- Metoclopramide is a widely used dopamine-receptor antagonist.
- It enhances upper gastrointestinal motility and is prescribed for nausea and vomiting.
Observation:
- A case of hypertensive crisis is reported in a 76-year-old male patient.
- The patient was administered metoclopramide at a dosage of 30 mg daily.
Findings:
- The administration of metoclopramide was associated with the development of a hypertensive crisis.
- This highlights a potential serious adverse drug reaction.
Implications:
- Clinicians should be aware of the risk of hypertensive crisis with metoclopramide.
- Careful patient monitoring is essential, especially in elderly individuals or those with pre-existing cardiovascular conditions.
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