Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Drug resistant status epilepticus].

F Assal1, A Coeytaux, P Jallon

  • 1Unité d'EEG, clinique de neurologie, hôpital cantonal universitaire, Genève, Suisse.

Neurophysiologie Clinique = Clinical Neurophysiology
|August 5, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immune-cognitive relationships across viral infections: A transnosological systematic review.

Neuroscience and biobehavioral reviews·2026
Same author

Inflammatory predictors of Post-COVID fatigue.

Brain, behavior, & immunity - health·2025
Same author

Systemic cytokines related to memory function 6-9 months and 12-15 months after SARS-CoV-2 infection.

Scientific reports·2024
Same author

The encoding of speech modes in motor speech disorders: whispered versus normal speech in apraxia of speech and hypokinetic dysarthria.

Clinical linguistics & phonetics·2024
Same author

Corrigendum to "Acute TNFα levels predict cognitive impairment 6-9 months after COVID-19 infection" [Psychoneuroendocrinology 153 (2023) 106104].

Psychoneuroendocrinology·2023
Same author

Acute TNFα levels predict cognitive impairment 6-9 months after COVID-19 infection.

Psychoneuroendocrinology·2023

Refractory epileptic state (RES) involves severe seizures unresponsive to medication. Early diagnosis is crucial to differentiate RES from other conditions and treat underlying causes for better outcomes.

Area of Science:

  • Neurology
  • Epileptology
  • Critical Care Medicine

Context:

  • Refractory epileptic state (RES) presents a significant clinical challenge due to its resistance to standard antiepileptic drug treatments.
  • Accurate differentiation from conditions like pseudo-seizures and encephalopathies with triphasic waves is critical for appropriate management.
  • RES is often indicative of underlying focal brain lesions or severe systemic diseases, particularly metabolic disorders.

Purpose:

  • To define refractory epileptic state (RES) and highlight the importance of early diagnostic distinction.
  • To discuss the common underlying etiologies of RES, including focal brain lesions and metabolic diseases.
  • To address the nosographic classification of Periodic Lateralized Epileptiform Discharges (PLEDs) as a related area requiring further investigation.

Related Experiment Videos

Summary:

  • Refractory epileptic state (RES) is characterized by severe, drug-resistant seizures.
  • Distinguishing RES from pseudo-seizures and encephalopathies is essential for timely and correct treatment.
  • Treatment focuses on addressing the root cause, such as metabolic imbalances or brain lesions.
  • The article also touches upon the debated topic of Periodic Lateralized Epileptiform Discharges (PLEDs).

Impact:

  • Improved diagnostic accuracy for refractory epileptic state, leading to more targeted therapeutic interventions.
  • Enhanced understanding of the underlying causes of severe, intractable epilepsy.
  • Clarification of diagnostic criteria and potential therapeutic pathways for patients with RES.
  • Contribution to the ongoing discussion regarding the classification and management of PLEDs.