Mouse mononuclear cell chemotaxis: description of system

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D A Boetcher, M S Meltzer

Journal of the National Cancer Institute

|March 1, 1975

Abstract:

The mononuclear cell chemotaxis assay was adapted for use with normal mouse peritoneal cells. Mouse peritoneal macrophages responded well to endotoxinactivated mouse serum and to chemotactic factors produced by mouse spleen cell cultures stimulated with mitogens or specific antigen. The assay was quantitative, reproducible, and applicable to several mouse strains.

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