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Relationship Formation02:12

Relationship Formation

What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
Preparation of Diols and Pinacol Rearrangement01:57

Preparation of Diols and Pinacol Rearrangement

Compounds bearing two hydroxyl groups are known as diols. When the hydroxyl groups are located on adjacent carbon atoms, the diols are called vicinal diols or glycols. Under acidic conditions, vicinal diols undergo a specific reaction called pinacol rearrangement.
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[3,3] Sigmatropic Rearrangement of 1,5-Dienes: Cope Rearrangement01:21

[3,3] Sigmatropic Rearrangement of 1,5-Dienes: Cope Rearrangement

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Aldol Condensation with β-Diesters: Knoevenagel Condensation01:27

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Moment of a Couple: Problem Solving01:30

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Related Experiment Video

Updated: Jul 6, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
07:20

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Candida's arranged marriage.

N A Gow1, A J Brown, F C Odds

  • 1Department of Molecular and Cell Biology, University of Aberdeen, Aberdeen AB25 2ZD, UK. n.gow@abdn.ac.uk

Science (New York, N.Y.)
|August 5, 2000
PubMed
Summary

The fungus Candida albicans was long thought to reproduce only asexually. Recent genomic studies revealed a mating type locus, leading to the discovery of actual mating in this important fungal pathogen.

Area of Science:

  • Mycology
  • Fungal Genetics
  • Microbiology

Background:

  • Candida albicans is a fungus commonly studied by biologists.
  • It was traditionally believed to reproduce solely through asexual means.
  • Lack of observed mating, meiosis, or a haploid stage supported asexual reproduction assumptions.

Purpose of the Study:

  • To investigate the reproductive mechanisms of Candida albicans.
  • To explore the implications of genomic sequencing on understanding fungal reproduction.
  • To confirm the existence and function of a potential mating type locus.

Main Methods:

  • Genome sequencing of Candida albicans.
  • Analysis of the identified mating type locus.
  • Experimental demonstration of fungal mating.

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Main Results:

  • Genomic sequencing revealed a potential mating type locus in C. albicans.
  • Subsequent research confirmed the existence of actual mating in the fungus.
  • This challenges previous assumptions about its reproductive strategies.

Conclusions:

  • Candida albicans is capable of sexual reproduction.
  • The discovery of mating in C. albicans alters our understanding of its biology.
  • This finding has significant implications for fungal research and potential therapeutic strategies.