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Clinical outcome of patients with internal carotid artery occlusion: a prospective follow-up study

F Verlato1, G Camporese, E Bernardi

  • 1Unit Care of Angiology and the Emergency Care Unit, University Hospital of Padua, Italy.

Journal of Vascular Surgery
|August 5, 2000
PubMed

Insights

Internal carotid artery (ICA) occlusion appears to be a benign condition, regardless of symptoms or contralateral carotid artery narrowing. Patients with ICA occlusion had low rates of mortality and no nonfatal cerebrovascular events.

Area of Science:

  • Vascular Neurology
  • Cerebrovascular Disease
  • Carotid Artery Disease

Background:

  • Internal carotid artery (ICA) occlusion is a significant risk factor for stroke.
  • The clinical impact of ICA occlusion can vary based on presentation and contralateral carotid system status.

Purpose of the Study:

  • To evaluate the impact of clinical presentation (symptomatic vs. asymptomatic) on mortality and cerebrovascular events in patients with ICA occlusion.
  • To determine if contralateral atherosclerotic narrowing affects outcomes in patients with ICA occlusion.

Main Methods:

  • Prospective cohort study of 41 consecutive patients with objectively documented ICA occlusion.
  • Patients were followed for a mean of 44.5 months.
  • Contralateral carotid artery stenosis was assessed, with severe stenosis (>75%) prompting intervention.

Main Results:

  • Overall mortality rate was 22.0%; stroke-related mortality was 7.3%.
  • No significant differences in mortality were observed between symptomatic and asymptomatic patients.
  • No nonfatal cerebrovascular events occurred in any patient.

Conclusions:

  • Internal carotid artery (ICA) occlusion is generally a benign condition, irrespective of symptomatic or asymptomatic presentation.
  • Contralateral internal carotid artery (ICA) stenosis below 75% does not appear to worsen the prognosis.
Abstract

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