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Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies
Published on: January 11, 2019
A neurophysiological grading scale for carpal tunnel syndrome
1Kent and Canterbury Hospital, Canterbury, Kent, England. Jeremy.Bland@kch-tr.sthames.nhs.uk
Muscle & Nerve
|August 3, 2000
Summary
This study introduces a standardized neurophysiological grading scale for carpal tunnel syndrome (CTS) severity. The scale shows a strong correlation between clinical history scores and nerve conduction study findings for CTS patients.
Area of Science:
- Neurology
- Neurophysiology
Background:
- Carpal tunnel syndrome (CTS) severity is currently expressed using varied methods in literature and clinical practice.
- A need exists for a consistent and objective measure of CTS severity.
Purpose of the Study:
- To document patient distribution across a novel neurophysiological grading scale for carpal tunnel syndrome (CTS).
- To establish the relationship between clinical history and objective nerve conduction study findings in CTS.
Main Methods:
- Development of a grading scale (0-6) based on nerve conduction study (NCS) findings.
- Assessment of NCS parameters including sensory nerve conduction velocity, terminal motor latency, and abductor pollicis brevis (APB) response.
- Correlation of neurophysiological grades with a numerical score derived from clinical history.
Main Results:
- A highly significant linear relationship was observed between neurophysiological grading and clinical history scores.
- Patients with more characteristic CTS symptoms generally presented with higher neurophysiological grades.
- The proposed scale provides objective categorization of CTS severity, independent of specific laboratory normal values.
Conclusions:
- The developed neurophysiological grading scale offers a reliable method for quantifying carpal tunnel syndrome severity.
- This scale demonstrates a strong correlation with clinical presentation, aiding in objective patient assessment.
- The scale's independence from specific laboratory norms enhances its clinical applicability and consistency.

