Related Experiment Video
Updated: Aug 17, 2026

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
Primary hypertrophic colonopathy
M Janaki1, K P Chandrasekhar, G M Rao
1Department of Pathology, Kurnool Medical College/Govt General Hospital.
Abstract:
We report a 45-year-old man and a 60-year-old woman who presented with features of intermittent intestinal obstruction. Barium enema revealed narrowing at the pelvic-rectal junction in the man, and from the pelvic colon to the anal verge in the woman. Histology of the resected sections showed marked hypertrophy of the muscularis propria in both cases, with normal mucosa, submucosa and myenteric plexus. Both patients are asymptomatic at 4 years' and 2 years' follow up. This entity of primary hypertrophic colonopathy may be a variant of primary visceral myopathy.
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