Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pediatric autoimmune cardiovascular disease.

A H Rees1

  • 1Department of Pediatrics, University of Louisville School of Medicine, KY, USA.

The Journal of the Kentucky Medical Association
|August 5, 2000
PubMed
Summary

Pediatric autoimmune cardiovascular diseases pose severe risks to children, affecting heart valves, muscle, and surrounding tissues. These conditions, including rheumatic heart disease and Kawasaki disease, can lead to life-threatening complications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Taussig-Bing anomaly: arterial switch versus Kawashima intraventricular repair.

The Annals of thoracic surgery·1996
Same author

Transtelephonic echocardiography: successful use in a tertiary pediatric referral center.

The Journal of pediatrics·1993
Same author

Competitive antagonism of glutamate receptor channels by substituted benzazepines in cultured cortical neurons.

Molecular pharmacology·1992
Same author

Echocardiography for evaluating anatomic repair of transposition of the great arteries.

Southern medical journal·1992
Same author

Two-dimensional echocardiographic assessment of intracardiac masses in infants and children.

Southern medical journal·1991
Same author

Surgical approach to atrial septal defect in the female. Right thoracotomy versus sternotomy.

The American surgeon·1990

Area of Science:

  • Cardiovascular Medicine
  • Pediatric Rheumatology
  • Immunology

Background:

  • Autoimmune diseases can manifest with serious cardiovascular complications in children.
  • Conditions like rheumatic heart disease, lupus erythematosus, and juvenile rheumatoid arthritis are associated with cardiac involvement.
  • Specific vasculitides such as polyarteritis nodosa, Takayasu arteritis, and Kawasaki disease can affect coronary arteries.

Observation:

  • Pediatric autoimmune cardiovascular disease presents significant risks.
  • Valvular, myocardial, and pericardial structures are vulnerable to autoimmune attack.
  • Coronary arteries are particularly susceptible in certain pediatric vasculitides.

Findings:

  • Autoimmune conditions frequently lead to severe cardiac sequelae in pediatric patients.
  • Morbidity and mortality are linked to valvular, myocardial, and pericardial damage from rheumatic heart disease, lupus, and juvenile rheumatoid arthritis.
  • Life-threatening coronary artery issues arise in childhood polyarteritis nodosa, Takayasu arteritis, and Kawasaki disease.

Implications:

  • Early recognition and management of pediatric autoimmune cardiovascular disease are crucial.
  • Understanding the specific cardiac manifestations aids in targeted treatment strategies.
  • Further research into the pathogenesis and therapeutic interventions for these conditions is warranted.

Related Experiment Videos