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Synthesis and antisecretory activity of 6-substituted 5-cyanomethylimidazo[2,1-b]thiazoles and
A Andreani1, A Leoni, A Locatelli
1Dipartimento di Scienze Farmaceutiche, Università di Bologna, Italy. aldoandr@alma.unibo.it
Arzneimittel-Forschung
|August 5, 2000
Abstract:
The synthesis of imidazo[2,1-b]thiazole and imidazo[2,1-b][1,3,4]thiadiazole derivatives, related to known antiulcer agents, is reported. 5-Cyanomethyl-6-methylimidazo[2,1-b]thiazole showed significant antisecretory activity in the isolated rabbit gastric glands assay.