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Paleolithic vs. modern diets--selected pathophysiological implications.

S B Eaton1, S B Eaton

  • 1Dept Anthropology, Emory University, Atlanta, GA 30327, USA. sboydeaton@aol.com

European Journal of Nutrition
|August 5, 2000
PubMed
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Humans remain genetically adapted to the Paleolithic diet of wild game, fish, and plants. Modern diets differ significantly, impacting health and disease risk.

Area of Science:

  • Evolutionary biology
  • Nutritional science
  • Human genetics

Background:

  • Human genetic evolution was significantly influenced by Paleolithic nutritional patterns.
  • Modern human genomes show minimal change since the advent of agriculture, suggesting continued adaptation to ancestral diets.

Observation:

  • Paleolithic diets were rich in protein, fiber, micronutrients, and phytochemicals.
  • Key differences from Western diets include fat profile, carbohydrate sources (fruits/vegetables vs. cereals/sugars), and absence of dairy.
  • These dietary distinctions have significant pathophysiological implications.

Findings:

  • The review examines phytochemicals and cancer risk.
  • It explores the relationship between calcium, physical activity, bone density, and geometry.

Related Experiment Videos

  • Further findings cover protein, potassium, acid secretion, urinary calcium, sarcopenia, adiposity, and insulin resistance.

    • Implications:

    • Understanding Paleolithic nutrition offers a basis for novel, testable hypotheses grounded in evolutionary theory.
    • This perspective challenges complacency with current nutritional guidelines.
    • It highlights potential avenues for disease prevention and health optimization.