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Published on: March 28, 2025
Conversion factors in laparoscopic cholecystectomy for acute cholecystitis
J P Teixeira1, A C Saraiva, A C Cabral
1Hospital S. João, Department of Surgery II, Porto, Portugal.
Hepato-Gastroenterology
|August 5, 2000
Summary
Laparoscopic cholecystectomy for acute cholecystitis is effective, but factors like fever, high white blood cell count, and delayed surgery increase conversion rates. Early intervention within 4 days improves outcomes.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Clinical Outcomes
Background:
- Laparoscopic cholecystectomy is a standard treatment for acute cholecystitis.
- High conversion rates from laparoscopic to open surgery are frequently reported.
- Identifying preoperative factors predicting conversion is crucial for surgical planning.
Purpose of the Study:
- To assess preoperative factors associated with conversion during laparoscopic cholecystectomy for acute cholecystitis.
- To identify predictors of conversion to improve surgical decision-making.
Main Methods:
- A retrospective study of 100 laparoscopic cholecystectomies for acute cholecystitis.
- Analysis of preoperative parameters including patient demographics, ultrasound findings, bile cultures, and time to surgery.
- Statistical analysis (univariate and multivariate) to identify significant predictors of conversion.
Main Results:
- Preoperative factors significantly associated with conversion included gallbladder "plastron", fever >38°C, leukocytosis, delayed surgery, pericholecystic fluid, and Klebsiella in bile.
- Multivariate analysis identified leukocytosis and time to surgery as independent predictors of conversion.
- Age, sex, comorbidities, and gallbladder pathology did not show significant differences between converted and non-converted cases.
Conclusions:
- Laparoscopic cholecystectomy is a safe and effective treatment for acute cholecystitis.
- Performing the procedure within the first 4 days of diagnosis is recommended.
- Preoperative identification of factors like leukocytosis and delayed presentation can help anticipate conversion needs.

