Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Analytical validation in erythrocyte immunohematology].

L Mannessier1, F Roubinet, M Delamaire

  • 1EFS Nord-de-France, Lille, France.

Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine
|August 5, 2000
PubMed
Summary

Preventing hemolytic transfusion reactions requires rigorous immunohematologic testing. Ensuring the reliability of these tests involves careful reagent selection, validation, and consistent quality control measures.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification of Frailty in a Population of Former Immigrant Workers in the South of France.

The journal of nutrition, health & aging·2021
Same author

Population structure of modern-day Italians reveals patterns of ancient and archaic ancestries in Southern Europe.

Science advances·2019
Same author

[Structural or functional relationship between immunohematology and distribution - Which elements for controlling risks?]

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine·2019
Same author

[Impact of menstrual blood self-representation on contraceptive choice of women].

Gynecologie, obstetrique, fertilite & senologie·2019
Same author

Relevance and costs of RHD genotyping in women with a weak D phenotype.

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine·2018
Same author

Reference values for T, B and NK human lymphocyte subpopulations in adults.

Data in brief·2017

Area of Science:

  • Transfusion Medicine
  • Immunology
  • Clinical Laboratory Science

Background:

  • Hemolytic reactions due to anti-erythrocyte antibodies are a significant immunological risk in transfusional and fetomaternal settings.
  • These reactions, caused by incompatible blood transfusions or maternal-fetal antibody interactions, pose serious clinical consequences.

Purpose of the Study:

  • To highlight the critical importance of immunohematologic analyses in preventing hemolytic transfusion reactions.
  • To emphasize the necessity of robust methodological practices and quality control in these essential laboratory tests.

Main Methods:

  • Review of established immunohematologic analysis protocols.
  • Discussion of key elements influencing test reliability: reagent selection and validation, reception validation, secondary preparation controls, and daily internal controls.

Related Experiment Videos

  • Emphasis on the management of potential analytical anomalies.

    • Main Results:

    • Immunohematologic analyses are legislated due to their critical clinical impact.
    • Multiple factors contribute to the reliability of these analyses, including reagent quality, validation processes, and consistent control procedures.
    • Effective management of anomalies is crucial for accurate results.

    Conclusions:

    • Strict adherence to validated immunohematologic testing procedures is paramount for patient safety.
    • Comprehensive quality control, from reagent validation to daily checks, is essential for minimizing transfusion risks.
    • Proactive management of analytical issues ensures the integrity of immunohematologic testing.