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Related Experiment Videos

Mycophenolic acid in silage.

I Schneweis1, K Meyer, S Hörmansdorfer

  • 1Institute of Animal Hygiene, Faculty of Agriculture and Horticulture, Technische Universität München, 85354 Freising-Weihenstephan, Federal Republic of Germany.

Applied and Environmental Microbiology
|August 5, 2000
PubMed
Summary

Mold contamination in silage is common, with many samples containing Penicillium roqueforti. This mold produces mycophenolic acid, a compound that can suppress the immune system in livestock, potentially increasing disease susceptibility.

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Area of Science:

  • Agricultural Science
  • Mycology
  • Veterinary Medicine

Background:

  • Silage is a crucial feed for livestock, but its quality can be compromised by mold growth.
  • Certain molds produce mycotoxins that pose health risks to animals.

Purpose of the Study:

  • To investigate the prevalence of mold contamination in silage samples.
  • To quantify the presence of mycophenolic acid, a mycotoxin produced by Penicillium roqueforti.
  • To assess the potential health implications for livestock fed contaminated silage.

Main Methods:

  • Analysis of 233 silage samples for mold presence and enumeration.
  • Detection and quantification of mycophenolic acid using liquid chromatography-mass spectrometry.
  • Evaluation of mycotoxin levels in relation to established health risks.

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Main Results:

  • Molds were detected in 206 out of 233 (88.4%) silage samples.
  • Mycophenolic acid was found in 74 (32%) of the analyzed samples, with levels up to 35,000 microg/kg.
  • The mean concentration of mycophenolic acid was 1,400 microg/kg.

Conclusions:

  • A significant portion of silage samples are contaminated with molds, including Penicillium roqueforti.
  • The presence of immunosuppressive mycophenolic acid in silage raises concerns about livestock health.
  • Feeding contaminated silage may increase the risk of infectious diseases in livestock due to immune suppression.