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[Multiple sclerosis: descriptive study of its clinical forms in 302 cases]
M A Moreira1, E Felipe, M F Mendes
1Centro de Atendimento e Tratamento da Esclerose Múltipla, Clínica Neurológica, Faculdade de Ciências Médicas, Santa Casa de Misericórdia de São Paulo, Brazil. neurologia@santacasasp.org.br
Arquivos De Neuro-Psiquiatria
|August 2, 2000
Summary
This study on multiple sclerosis (MS) in 302 patients reveals common initial symptoms like sensory and visual issues. A significant finding is that 19.8% of patients experienced benign MS, indicating a favorable prognosis.
Area of Science:
- Neurology
- Epidemiology
Context:
- Multiple sclerosis (MS) is a leading cause of chronic neurologic disability in young adults.
- Understanding MS epidemiology is crucial for effective management and patient care.
Purpose:
- To retrospectively analyze the epidemiological characteristics, clinical manifestations, and disability progression in a cohort of 302 MS patients.
- To identify prognostic factors, including the prevalence of benign MS.
Summary:
- The study analyzed 302 MS patients, with an average age of 37.7 and a 3.13F:1M gender ratio.
- The average age of MS onset was 29.6. Relapsing-remitting MS (72%) was more common than progressive forms (28%).
- Initial symptoms were predominantly sensory (31.7%) and optical (26.8%), while later symptoms involved pyramidal (72.5%) and spinal cord (64.9%) systems. The average final EDSS was 3.37, and 19.8% had benign MS.
Impact:
- Findings align with global MS literature, highlighting the importance of recognizing benign MS for prognostic assessment.
- Provides valuable data on MS demographics, clinical presentation, and disability in a specific patient cohort.
- Contributes to a better understanding of MS natural history and informs clinical practice regarding patient outcomes.