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[Fatigue in multiple sclerosis relapsing-remitting form].

M F Mendes1, H P Tilbery, S Balsimell

  • 1Centro de Atendimento e Tratamento de Esclerose Múltipla, Departamento de Medicina, Faculdade de Ciências Médicas, Santa Casa de São Paulo, Brazil.

Arquivos De Neuro-Psiquiatria
|August 2, 2000
PubMed
Summary

Fatigue impacts over two-thirds of multiple sclerosis patients. Anxiety and disease duration predict fatigue, while expanded disability status scale scores correlate with its severity.

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Area of Science:

  • Neurology
  • Clinical Psychology

Context:

  • Multiple Sclerosis (MS) is a chronic neurological disease.
  • The remitting-relapsing form (RRMS) is the most common type.
  • Fatigue is a prevalent and often debilitating symptom in MS.

Purpose:

  • To investigate the prevalence and predictors of fatigue in RRMS patients.
  • To explore the relationship between fatigue severity and clinical factors.

Summary:

  • This study evaluated 95 patients with RRMS using the Fatigue Severity Scale.
  • Fatigue was present in 67.4% of the participants.
  • While gender, age, depression, and functional incapacity were not predictive, anxiety and disease duration showed a correlation with fatigue occurrence.
  • Higher Expanded Disability Status Scale (EDSS) scores correlated with increased fatigue severity.

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Impact:

  • Highlights the significant burden of fatigue in RRMS.
  • Identifies anxiety and disease duration as key factors associated with fatigue.
  • Suggests EDSS as a potential indicator for fatigue severity in MS management.
  • Informs clinical practice and future research on managing fatigue in multiple sclerosis.