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Mutations in the rpoB gene of multidrug-resistant Mycobacterium tuberculosis isolates from Brazil
A R Valim1, M L Rossetti, M O Ribeiro
1Laboratório Central do Rio Grande do Sul, Fundação Estadual de Produção e Pesquisa em Saúde, Porto Alegre-Rio Grande do Sul CEP 90130-001, Brazil.
Journal of Clinical Microbiology
|August 2, 2000
Abstract:
Mutations in a 69-bp region of the rpoB gene associated with rifampin resistance (Rif(r)) in 100 isolates (82 Rif(r)) from three states of Brazil were studied. Twenty-one different kinds of mutations were identified in the Rif(r) isolates, and six new alleles are described.