Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Brachial plexopathy associated with diffuse edematous scleroderma.

L Mouthon1, C Halimi, J C Dussaule Md

  • 1Department of Internal Medicine, Hôpital Avicenne and Paris-Nord University, 125, route de Stalingrad, 93000 Bobigny, France. luc.mouthon@avc.ap-hop-paris.fr

Annales De Medecine Interne
|August 3, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neoadjuvant ipilimumab and nivolumab for resectable stage II mucosal melanoma.

Annales de dermatologie et de venereologie·2025
Same author

[Combined folded paramedian forehead flap in extensive nasal tissue losses: A technical note].

Annales de chirurgie plastique et esthetique·2025
Same author

Use of perfusion device for free flap salvage after ischemia in swine.

Annales de chirurgie plastique et esthetique·2024
Same author

PD-L1 expression in the microenvironment and the response to checkpoint inhibitors in head and neck squamous cell carcinoma.

Oncoimmunology·2020
Same author

Dietary calcium impairs tomato lycopene bioavailability in healthy humans.

The British journal of nutrition·2017
Same author

Chitosan solutions as injectable systems for dermal filler applications: Rheological characterization and biological evidence.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2016

Systemic sclerosis (SSc) rarely affects the peripheral nervous system (PNS). This case study shows successful treatment of brachial plexus involvement in SSc using cyclophosphamide therapy.

Area of Science:

  • Rheumatology
  • Neurology
  • Dermatology

Background:

  • Systemic sclerosis (SSc) is a rare autoimmune disease affecting connective tissues.
  • Peripheral nervous system (PNS) involvement in SSc is uncommon, typically presenting as nerve entrapment.
  • Previous reports of SSc-related brachial plexus involvement are extremely limited.

Observation:

  • A 61-year-old woman with limited cutaneous SSc developed new-onset motor deficiency in her left arm.
  • The neurological deficit occurred alongside diffuse edematous skin changes.
  • No evidence of trauma or external compression of the brachial plexus was found.

Findings:

  • Intravenous pulse cyclophosphamide therapy was administered for six months.
  • Significant improvement in both skin manifestations and neurological deficits was observed.

Related Experiment Videos

  • This suggests a potential therapeutic response to cyclophosphamide in SSc-associated brachial plexopathy.

    • Implications:

    • This case highlights a rare presentation of SSc affecting the brachial plexus.
    • Cyclophosphamide therapy may be a viable treatment option for such neurological complications.
    • Further research is warranted to understand the mechanisms and efficacy of immunosuppressive therapy in SSc-related neuropathy.