Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pseudo-random procedures for rapid presentation rates using optical imaging and spectroscopy.

J Martindale1, J Berwick, D Johnston

  • 1Department of Academic Radiology, University of Sheffield, UK.

Neuroreport
|August 3, 2000
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Increased leucine turnover in women during the third trimester of uncomplicated pregnancy.

Metabolism: clinical and experimental·2004
Same author

Spontaneous, elicited and cued causal attributions in the year following a first myocardial infarction.

British journal of health psychology·2003
Same author

Distance-dependent modifiable threshold for action potential back-propagation in hippocampal dendrites.

Journal of neurophysiology·2003
Same author

Relation between insulin kinetics and insulin sensitivity in pregnancy.

European journal of clinical investigation·2003
Same author

Effects of the Magenstrasse and Mill operation for obesity on plasma plasminogen activator inhibitor type 1, tissue plasminogen activator, fibrinogen and insulin.

Pathophysiology of haemostasis and thrombosis·2002
Same author

Irish X-ray departments demonstrate varying levels of adherence to European guidelines on good radiographic technique.

The British journal of radiology·2002

This study introduces an event-related optical imaging procedure for rat barrel cortex. The novel method enhances statistical power for functional cortical architecture mapping, enabling direct comparison with other imaging modalities.

Area of Science:

  • Neuroscience
  • Optical Imaging
  • Cortical Function

Background:

  • Optical imaging provides detailed spatio-temporal maps of functional cortical architecture in the rat barrel cortex.
  • Existing methods may benefit from enhanced statistical power and direct comparison capabilities with other imaging modalities.

Purpose of the Study:

  • To describe an event-related procedure (ERP) for optical imaging using selective signal averaging.
  • To enable greater statistical power per unit time for functional imaging studies.
  • To allow direct comparison of event-related optical imaging studies with other imaging modalities.

Main Methods:

  • Utilized an anti-correlative pseudo-random event sequence with 1s vibrissal stimulation at 5 Hz and a 2s inter-event interval.
  • Employed selective signal averaging for event-related optical imaging.

Related Experiment Videos

  • Developed a spectral analysis method for locating barrel activity by analyzing summed event data.

    • Main Results:

    • Spatio-temporal characteristics of single wavelength and spectrographic results were comparable to standard techniques.
    • A general lessening of the haemodynamic response function (HRF) was observed.
    • Spectral analysis of remitted light from the barrel region showed a peak power spectrum near the inter-event interval frequency (+/- 0.12 Hz).

    Conclusions:

    • The described event-related optical imaging procedure offers enhanced statistical power for functional cortical architecture mapping.
    • The method facilitates direct comparison with other imaging modalities.
    • Spectral analysis provides an effective means for locating barrel activity within the cortex.